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Drugs of Choice
Allylamines
- Terbinafine
- Amorolfine
- Butenafine
Azoles
- Fluconazole
- Itraconazole
- Ketoconazole
- Ravuconazole
- Posaconazole
- Voriconazole
Antimetabolites
- Flucytosine
Glucan Synthesis Inhibitors
- Caspofungin
- Micafungin
- Anidulafungin
Polyenes
- Amphotericin B
- Amphotericin B Colloidal Dispersion (ABCD)
- Amphotericin B Lipid Complex (ABLC)
- Liposomal Amphotericin B (L-AMB)
- Amphotericin B Oral Suspension
- Liposomal Nystatin
Topical Agents
Miscellaneous systemic agents
- Griseofulvin
Antifungal pharmacology
Nephrotoxicity
Drug dosing in renal and liver dysfunction
Drug interactions
Therapeutic drug monitoring
Antifungal therapy cost analysis
Pharmacoeconomic analysis of antifungal therapy
Content Director:
Russell E. Lewis, Pharm.D.
Allylamines
The only member of this group is terbinafine, and this agent acts by inhibiting squalene epoxidase. This is another enzyme in the pathway that leads to synthesis of ergosterol, so this agent is conceptually related to the azole antifungal agents.
Terbinafine
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